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Vaccination: Varicella-Zoster Virus Vaccine
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Total 2054 results found since Jan 2013.
Evaluating public interest in herpes zoster in Germany by leveraging the internet: a retrospective search data analysis
CONCLUSIONS: The study demonstrated that evaluating internet search data is a viable method for assessing public interest in HZ, thereby identifying areas of unmet need to support targeted public health campaigns.PMID:37580664 | DOI:10.1186/s12889-023-16463-4
Source: Herpes - August 14, 2023 Category: Infectious Diseases Authors: Alphina Kain Linda Tizek Hannah Wecker Fabian Walln öfer Tilo Biedermann Alexander Zink Source Type: research
Exploring the purine core of 3'-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics.
Abstract
A series of new nucleoside analogues based on a C-3 branched ethynyl sugar derivative as present in 3'-C-ethynylcytidine (ECyd) and -adenosine (EAdo), combined with modified purine bases was synthetized and evaluated against a broad array of viruses and tumour cell lines. The pronounced cytostatic activity of EAdo was confirmed. EAdo and its 2,6-diaminopurine analogue showed inhibitory activity against vaccinia virus (EC50: 0.31 and 51μM, respectively). Derivative 10 on the other hand was found active against varicella zoster virus (EC50: 4.68μM).
PMID: 26965865 [PubMed - as supplied by publisher]
Source: Bioorganic and Medicinal Chemistry Letters - March 3, 2016 Category: Chemistry Authors: Hulpia F, Balzarini J, Schols D, Andrei G, Snoeck R, Van Calenbergh S Tags: Bioorg Med Chem Lett Source Type: research
Herpes zoster and the search for an effective vaccine.
This article reviews VZV pathogenesis, host responses and current vaccines available to prevent herpes zoster. This article is protected by copyright. All rights reserved.
PMID: 27164323 [PubMed - as supplied by publisher]
Source: Clinical and Developmental Immunology - May 9, 2016 Category: Allergy & Immunology Authors: Arnold N, Messaoudi I Tags: Clin Exp Immunol Source Type: research
SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis
Christine I. Alston1,2 and Richard D. Dix1,2*
1Department of Biology, Viral Immunology Center, Georgia State University, Atlanta, GA, United States
2Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States
Suppressor of cytokine signaling (SOCS) proteins provide selective negative feedback to prevent pathogeneses caused by overstimulation of the immune system. Of the eight known SOCS proteins, SOCS1 and SOCS3 are the best studied, and systemic deletion of either gene causes early lethality in mice. Many viruses, including herpesviruses such as herpes simplex virus and cytomega...
Source: Frontiers in Immunology - April 10, 2019 Category: Allergy & Immunology Source Type: research
Role of Multivalency and Antigenic Threshold in Generating Protective Antibody Responses
Mark K. Slifka1* and Ian J. Amanna2
1Division of Neuroscience, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, United States2Najít Technologies, Inc., Beaverton, OR, United States
Vaccines play a vital role in protecting our communities against infectious disease. Unfortunately, some vaccines provide only partial protection or in some cases vaccine-mediated immunity may wane rapidly, resulting in either increased susceptibility to that disease or a requirement for more booster vaccinations in order to maintain immunity above a protective level. The durabilit...
Source: Frontiers in Immunology - April 30, 2019 Category: Allergy & Immunology Source Type: research
Vaccination against the herpes zoster virus
CONCLUSIONS: We have a safe and effective vaccine against the herpes zoster virus that allows us to protect the most vulnerable population groups against this virus.PMID:37573820 | PMC:PMC10428030 | DOI:10.1016/j.aprim.2023.102710
Source: Atencion Primaria - August 13, 2023 Category: Primary Care Authors: Jos é Javier Gómez Marco Susana Mart ín Martín Pablo Aldaz Herce Ana Pilar Javierre Miranda Coro S ánchez Hernández Source Type: research
